According to details, the blast occurred inside a bus at Dukani Baba Chowk at Saryab Road, killing eleven persons at least including two children.
Meanwhile, rescue teams rushed to the site and shifted the injured to Civil Hospital Quetta. It was further said that six of the wounded are in precarious condition.
Heavy contingents of police and Frontier Corps (FC) have cordoned off the site and searching for evidence.
Authorities fear rise in casualties as the bus carried 40 passengers at the time of incident.
Meanwhile, Home Minister Sarfaraz Bugti has strongly condemned the incident, while CM Balochistan Dr Abdul Malik Baloch termed it a ‘conspiracy to sabotage peace in the province’.