The Russian, who won the ATP World Tour Finals title in 2009 and helped his country win the Davis Cup in 2006, said injuries had forced him to end his 15-year career.
“I had a lot of injuries over the last few years,” Davydenko told a news conference in Moscow.
“They are still causing me discomfort. The time has come: I am officially announcing my retirement as a professionalsportsman.”
Davydenko, never one of the sport’s great showmen, consistently mixed it with the big guns and famously beat Roger Federer at the 13th time of asking in the semi-finals of the TourFinals in London five years ago before downing Argentina’s Juan Martin del Potro in the final.
His best year on tour, however, was in 2006 when he won five titles and reached the U.S. Open semi-final, rising to third in the world rankings.
He also reached the U.S. Open semi-finals the following year and made the last four at Roland Garros in 2005 and 2007.
In total, the baseline specialist known for his speed around the court and durability won 21 titles.