The Britain-based group said it was unclear if the raids on Aleppo’s Marjeh district were carried out by aircraft belonging to the Syrian government or its ally Russia.
The latest civilian deaths come as rebels press an assault intended to break a government siege of opposition-held Aleppo that began on July 17 and has raised fears of a humanitarian crisis.
In an audio message released Friday, Abu Mohamed al-Jolani, the head of Al-Qaeda’s former affiliate in Syria, pledged the operation would soon succeed.
The assault started on Sunday and is targeting the Ramussa district that contains the main supply route to the government-held west of the city.
Once Syria’s economic powerhouse, Aleppo has been ravaged by the war that began in March 2011 with anti-government protests.
After some initial advances, government forces backed by Russian air strikes have pushed back opposition fighters, which include jihadists from Jolani’s faction, now known as the Fateh al-Sham Front.
According to the Observatory, at least 112 civilians, including 33 children, have been killed in Aleppo since the rebel assault began on Sunday.
The deaths include 65 people, among them 22 children, killed in rebel fire on government neighbourhoods, the Observatory said.
Another 42 people, including 11 children, have been killed in strikes on eastern Aleppo, the monitor said.
It reported five more deaths in rebel fire on the Kurdish-majority Sheikh Maqsud district of the city.
In an audio message, Jolani said God had granted fighters “a glorious victory in the battle to break the siege of Aleppo.”
“This battle, the outcome of which will go beyond simply opening the road for the besieged, will change the balance of the conflict…setting the scene for a new stage of the battle,” he pledged.
Elsewhere in Aleppo province, the monitor said an alliance of Kurdish and Arab fighters was advancing inside the Islamic State bastion of Manbij.
Observatory chief Rami Abdul Rahman said the Syrian Democratic Forces (SDF) now held 70 percent of the town.
“The Islamic State has entered its final phase in the town of Manbij,” he told AFP, adding however that IS was keeping a number of civilians there as human shields.
“The progress the SDF has made in the last week is more than it was able to achieve in previous weeks put together.”
The SDF began an assault on Manbij in late May and entered the town on June 23, with support from the US-led coalition against IS.
Manbij sits on the route between the Turkish border and the eastern city of Raqa, the jihadists’ de facto capital in Syria.