If confirmed, his death could change the course of the Afghan insurgency, which had grown fiercer under Mansour’s leadership.
Who will succeed him?
Mansour was appointed head of the Taliban in July 2015 following the revelation that the group’s founder Mullah Omar had in fact been dead for two years.
He was widely blamed for leading the cover-up and the roster of candidates to succeed him will include many of the same names who entered the fray last year.
These include Omar’s son Mullah Yakoub, who was favoured by some commanders as new leader but at the time judged too young and inexperienced, and Omar’s brother Mullah Abdul Manan Akhund.
Mansour gave both of them senior positions on the group’s leadership council and both are seen as favourites to take over.
Another possible successor is Mansour’s deputy Sirajuddin Haqqani — leader of the feared Taliban-allied Haqqani network responsible for some of the worst attacks on Afghan and US targets.
“This could be the time Haqqanis will try to take over the whole movement,” said Pakistani security analyst Amir Rana.
Will this further splinter the Taliban?
Almost certainly yes. Mansour had been particularly effective at subduing dissidents and eliminating rivals.
Mullah Dadullah, a prominent dissident commander, was killed last year in a gunfight with Mansour loyalists. And Mullah Rassoul, who formed a Taliban breakaway faction, had reportedly been detained by the Pakistani military — though his followers continue to fight on in his name.
If Mansour is indeed dead, analysts believe differences are once again likely to surface within the militants.
How would this impact the security situation?
“This could help the peace process — if it allows the moderate faction to come to the surface,” said Ahmed Rashid, author of the book “Descent into Chaos”.
While infighting could buy some breathing space for beleaguered Afghan forces, the strategy of “divide and rule” may also backfire.
“First Mullah Omar and now Mansour — once you take the core out of a movement it could begin to unravel,” said Imtiaz Gul, director of the Islamabad based Centre for Research and Security Studies.
“On the other hand, peacemaking will become even more difficult if you are dealing with so many leaders. This has been the strategy for several years — to splinter them and make deals — but whether that works, we don’t know.”
According to Rana, Mansour’s death could also pave the way for groups like the Islamic State and Islamic Movement of Uzbekistan, long in the Taliban’s shadow, to emerge stronger than before.
What does the drone attack mean for Pakistan?
Pakistan was one of the Taliban’s main allies during their 1996-2001 rule of Afghanistan, and has continued to exert influence over their insurgency.
In March Pakistan’s top foreign affairs official Sartaj Aziz admitted openly what many had suspected for years — that the Afghan Taliban’s top leadership were sheltering inside the country.
But with peace efforts stalled despite the formation in January of a four-country group — the United States, China, Pakistan and Afghanistan — designed to kickstart the efforts, US patience could have been growing thin.
The fact that the strike took place deep inside Pakistani territory, and not in the border tribal regions where all but one previous such attack occurred, will raise speculation however that Islamabad acquiesced.
The last round of four-way talks took place in Islamabad Wednesday.
At that stage, the US was ostensibly still willing to talk to the Taliban and their leader. Omar’s intransigence may have been his downfall.
“There was an agreement that if Taliban refuse to come to the table then Pakistan will cooperate with operations against the Taliban. They had a commitment,” said analyst Rana.
