Soon after the explosion, police officials arrived at the spot and started a search operation in the area while a bomb disposal squad was also called in.
The explosion left a policeman injured, who was later shifted to a nearby hospital in Mardan, while the minister himself remained unhurt.
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The Awami National Party (ANP) leaders have been continual targets of militant outfits operating in the northwest region of Pakistan.
Ameer Haider Khan Hoti had also escaped a suicide attack that targeted his convoy in Mardan in February 2013.
