The latest attack has raised fears of a repeat of a deadly school attack five months ago that toughened country’s resolve to fight militants.
According to police, all teachers and children at high school for boys were safe after the gunmen killed the guard in the central town of Dera Ghazi Khan.
“We are still not sure how many gunmen were there and whether they are still inside. The police are searching,” district police officer Rehmat Ullah Khan Niazi told Reuters.
Pakistani Taliban militants killed 153 people, most of them children, at a high school in the northwestern city of Peshawar on Dec. 16.
That attack hardened Pakistan’s resolve to fight Islamist militants who have been battling the state for years.
There have been two grenade attacks on schools in the southern city of Karachi since early February though no one was hurt in either one.
Elsewhere on Monday, police rescued seven colleagues kidnapped by gunmen at a checkpoint the previous day.
READ: Bandits ambush police check-post, abduct seven cops
The abductors dumped the seven in a forest near the Indus river and fled as police scoured the area, said provincial interior minister Shuja Khanzada.
Police were hunting for the kidnappers. -Reuters
READ: Punjab, Sindh police launch joint operation to recover abducted cops