Police on a secret report conducted raid in Hub and arrested Agha Jami with his two accomplices.
Police captured illegal arms from the three accused.
Agha Jami said to be a right hand man of Arshad Pappu-the head of two main gangs involved in gang warfare in Lyari-who was later killed by the rival gang led by Uzair Baloch.
The other two accused were arrested on the indication of Agha Jami, police sources said.
Accused Agha Jami was wanted to Karachi and Hub poice in more than 50 heinous crimes including murder, police said.
Arrested accused have been transferred to an undisclosed place for interrogation, sources said.