The four-match test series is level at 1-1.
Pakistan’s tour to England started on a high as they beat the hosts at the historic Lords stadium by 75 runs.
However, the hosts came back in spectacular fashion as they beat the visitors by a whooping 330 runs at Manchester to level the series.
After the dismal show at Old Trafford, Pakistan is expected to make several changes to their side. Opener Sami Aslam is likely to be introduced in the side in place of Shan Masood.
Sohail Khan is also a likely replacement for left arm fast bowler Wahab Riaz.
Meanwhile, England have replaced injured all rounder Ben Stokes with pacer Steven Finn.
Pakistan (probable): Mohammad Hafeez, Sami Aslam, Azhar Ali, Younis Khan, Misbah-ul-Haq (capt), Asad Shafiq, Sarfraz Ahmed (wkt), Mohammad Amir, Yasir Shah, Sohail Khan and Rahat Ali.
England: Alastair Cook (capt), Alex Hales, Joe Root, James Vince, Gary Ballance, Jonny Bairstow (wkt), Moeen Ali, Chris Woakes, Stuart Broad, Steven Finn and James Anderson.