Son of Sher Muhammad Khan, Rana Sanaullah Khan was born on January 1, 1955 in Faisalabad, Punjab. He hails from a Rajput family. A practicing lawyer, he holds bachelors in commerce from Government College, Faisalabad and an LLB from Punjab Law College, Lahore.
After education, Sanaullah began his political career from his native town of Faisalabad. Initially, he entered Pakistan Peoples Party (PPP) later joining Pakistan Muslim League-Nawaz (PML-N).
He has been an elected member of the Punjab assembly four times since 1990 and has served as the deputy opposition leader and minister for law and parliamentary affairs.
In August 2011, Rana Sanaullah accused American Warren Weinstein of being an American spy although Weinstein had lived in Pakistan for seven years and there was no evidence that he was a spy.
Weinstein went missing a week later and was accidentally killed in a January 2015 US drone strike on the Afghanistan-Pakistan border, as announced by U.S. President Barack Obama at a White House press conference on April 23, 2015.