Zika research to be published rapidly, and free: statement

A statement signed by the journals Nature, Science and The Lancet, the Chinese Academy of Sciences, France’s Institut Pasteur, the Bill and Melinda Gates Foundation and the Japan Agency for Medical Research and Development said data was a crucial tool in fighting the public health emergency.

“Journal signatories will make all content concerning the Zika virus free to access,” the document said.

For their part, research funders will require scientists to share interim as well as final data as rapidly and widely as possible.

The route to publication can be a long, slow one, and research findings are usually not shared until after they have been published in a peer-reviewed journal.

“The arguments for sharing data, and the consequences of not doing so, have been thrown into stark relief by the Ebola and Zika outbreaks,” the document stated.

“In the context of a public health emergency of international concern, there is an imperative on all parties to make any information available that might have value in combatting the crisis.”

The statement urged other organisations to follow suit.

Other signatories included Doctors Without Borders (MSF in its French acronym), The New England Journal of Medicine, PLOS Science Journals, the South African Medical Research Council and the Wellcome Trust.

The move was welcomed by experts as a sea change in public health research.

– Life-saving –

Trudie Lang, director of the Global Health Network, said the response to Zika — even more so than in the case of Ebola — was being hamstrung by the many unknowns.

“We are still to prove that Zika causes microcephaly, and we need to know at what point damage happens in pregnancy, should this be the case,” she said in comments issued by the Science Media Centre in London.

“In addition we need to develop better diagnostic tools and agree how to interpret anomaly scans to assess how these affected babies are developing.”

Data needs to be shared as quickly as possible, she said, “to address all these questions concurrently.”

Lang also stressed the need to ensure the data is reliable and accurate.

This “requires research sites to be well trained and have the resources they need to collect and manage data in ways that avoid error,” she said.

Infectious diseases professor Mark Woolhouse from the University of Edinburgh described the commitment as one of the most welcome developments in decades.

“If acted upon, this declaration will save lives,” he said.

An outbreak of the usually benign Zika virus in Latin America and the Caribbean has coincided with a surge in babies with microcephaly, a condition that causes them to have unusually small heads and brains, leading to death or disability.

No scientific proof has been found that Zika causes microcephaly, though the UN’s World Health Organization (WHO) has said a link is “strongly suspected” and has declared Zika a “public health emergency of international concern.”

There is no cure or vaccine for the virus which, in most people, causes mild symptoms.