Spinner Jack Leach grabbed four wickets to help England dismiss Pakistan for 366 in their first innings on day two of the second Test in Multan on Wednesday.
The left-armer took 4-114 while pacers Brydon Carse finished with 3-50 and Matthew Potts 2-66 as Pakistan managed to add 107 after resuming the day on 259-5.
Debutant Kamran Ghulam top-scored with 118 and Saim Ayub made 77.
England lead the three-match series 1-0 after an innings and 47-run victory in the first Test, also in Multan.
