Sleep apnea severity linked to COVID-19 outcomes

The risk of severe illness from COVID-19 is higher in people with obstructive sleep apnea and other breathing problems that cause oxygen levels to drop during sleep, researchers say.

They tracked 5,402 adults with these problems and found that roughly a third of them eventually tested posted for the coronavirus.

While the chance of being infected did not increase with the severity of their problems, people with higher scores on the “apnea-hypopnia index” – a measure of the severity of their sleep-related breathing problems – had higher odds of needing to be hospitalized or dying from COVID-19, Drs. Cinthya Pena Orbea and Reena Mehra of the Cleveland Clinic and colleagues reported on Wednesday in JAMA Network Open.

It is not clear if treatments that improve sleep apnea, such as CPAP machines that push air into patients’ airways during sleep, would also reduce the risk of severe COVID-19, said Pene Orbea and Mehra.

Vaccines induce neutralizing antibodies in breast milk

Infants might benefit from COVID-19 antibodies in breast milk regardless of whether mothers acquired the antibodies from being infected with SARS-CoV-2 or from vaccines, according to new findings reported on Wednesday in JAMA Pediatrics.

Researchers studied antibodies in breast milk samples from 47 mothers who had been infected with the virus and 30 healthy mothers who had received the vaccines from Moderna or Pfizer.

Antibodies from both groups were able to neutralize active SARS-CoV-2 virus, and while antibodies from infection were evident in milk for longer periods, antibody levels from vaccination “were much more uniform,” said study leader Bridget Young of the University of Rochester School of Medicine and Dentistry in New York.

Thus, there is likely benefit to getting vaccinated even after a COVID-19 infection because breast milk would then contain a diverse variety of antibodies, she said.

The researchers did not study the effect of the antibodies on the babies who consumed the milk.

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